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COVID-19 and the Fourth Trimester

November 04, 2021

This episode highlights COVID-19’s impact on overdose-related deaths during the postpartum period, also known as the fourth trimester. There has been a significant increase in postpartum overdose-related deaths in recent years—a problem that has only been exacerbated by the COVID-19 pandemic.

In this episode, Kristina Box, MD (SHO-IN) discusses the topic from a state-level perspective. Mishka Terplan, MD (medical director, Friends Research Institute) then shares an overview of the stigma this population faces, and what can be done to improve health outcomes for people with substance use disorder during the postpartum period.

Show Notes


  • Kristina Box, MD, FACOG, Indiana State Health Commissioner
  • Mishka Terplan, MD, MPH, FACOG, DFASAM, Friends Research Institute